Virginia to host AstraZeneca’s largest-ever global manufacturing site, with AI-driven production and next-gen therapies

July 2025 – USA:
Global biopharma giant AstraZeneca has announced a bold plan to invest $50 billion in the United States by 2030, reinforcing its commitment to advancing medicine manufacturing and cutting-edge R&D across the country. This unprecedented investment is expected to create thousands of direct and indirect skilled jobs, supercharge clinical innovation, and accelerate next-generation treatments for American and global patients alike.

Building the Future: Virginia to Become a Global Hub for Pharma Manufacturing
At the heart of AstraZeneca’s plan is the construction of its largest global manufacturing facility in the Commonwealth of Virginia, designed to produce vital medicinal substances for its metabolic disease and weight management portfolio. The site will include technologies for small molecules, oral GLP-1, oral PCSK9 inhibitors, baxdrostat, peptides, and oligonucleotides.

The Virginia site will leverage AI, data analytics, and advanced automation to modernize and scale biopharma manufacturing. This facility is set to become a global benchmark for smart pharma production.

Strategic Expansion Across the U.S.

• Mount Vernon, Indiana  Continued manufacturing scale-up
• Coppell, Texas   Specialty manufacturing for high-demand therapies
• Gaithersburg, Maryland   New R&D powerhouse
• Rockville, MD & Tarzana, CA   Advanced cell therapy production
• Kendall Square, MA & Cambridge  Strengthened biopharma innovation centers

These investments will help AstraZeneca reach its $80 billion revenue target by 2030, with 50% of total sales projected to come from the U.S. market.

Leadership Reactions: Confidence in U.S. Biotech Potential
Howard Lutnick, U.S. Secretary of Commerce, expressed strong support:

“America has long relied on foreign pharmaceutical imports. AstraZeneca’s investment reshapes that narrative. Thanks to new trade and tariff strategies, the U.S. is becoming a global pharmaceutical production leader.”

Virginia Governor Glenn Youngkin added:

“We’re honored that Virginia was chosen for AstraZeneca’s most significant global investment. This project will drive tech innovation in pharma and unlock high-paying jobs across the state.”

Pascal Soriot, CEO of AstraZeneca, emphasized the global vision:

“This investment reflects our deep trust in America’s innovation ecosystem. We’re not only building facilities  we’re strengthening our mission to deliver transformative medicines to millions in the U.S. and around the world.”

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