The global rat and mouse model market, valued at $1.46 billion in 2023, is expected to reach $3.10 billion by 2034, growing at a compound annual growth rate (CAGR) of 7.10% from 2024 to 2034. This growth is driven by increasing research and development activities in pharmaceutical and healthcare sectors.

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Key Market Insights

1. Regional Insights
   • North America dominated the market with a 49.8% share in 2023.
   • The Asia Pacific region is projected to experience significant growth during the forecast period.
2. Segment Analysis
   • By Model and Services: The model segment held the largest market share in 2023, while the services segment is expected to grow at the fastest CAGR from 2024 to 2034.
   • By Application: The cancer segment was the largest market segment in 2023. Meanwhile, the genetic diseases segment is predicted to grow at the highest rate during the forecast period.
   • By End-Use: Pharmaceutical and biotechnology companies held the largest share of the market in 2023. However, contract research and manufacturing organizations are anticipated to grow at the fastest rate in the coming years.

Importance of Rat and Mouse Models in Medical Research

Rat and mouse models are essential for preclinical research, offering insights into various biological processes and disease mechanisms. While mice have historically been the preferred model, rats are gaining popularity in specialized fields like neurology due to their unique advantages. Advances in gene-editing tools have expanded the capabilities of creating disease models in these species, driving further market growth.

Role of AI in Enhancing Rat and Mouse Models

Artificial intelligence (AI) and machine learning (ML) are transforming preclinical studies involving rat and mouse models by:

• Analyzing complex datasets.
• Optimizing experimental design.
• Predicting outcomes.

Integrating AI with animal model data and clinical human data enhances the relevance of findings, bridging the gap between preclinical and clinical research. For instance, in June 2024, researchers created a virtual rat with an AI brain to simulate real rats’ movements, yielding new insights into brain function that could revolutionize neurology and robotics.

Notable Companies in the Rat and Mouse Model Market

Key players in this market include:

• Charles River Laboratories
• Ozgene Pty Ltd
• Cyagen
• Inotiv
• The Jackson Laboratory
• genOway
• Taconic Biosciences, Inc.
• Kind Lab
• Biomedical Research Models (Biomere)
• Janvier Labs
• Hera Biolabs
• SMOC (Shanghai Model Organisms Center)
• The University of Texas Health Science Center

Recent Innovations

• The University of Texas Health Science Center: In July 2024, researchers developed a humanized mouse model with a human-like immune system and gut microbiota, which can generate specific antibody responses. This innovation is expected to advance immunotherapy and disease model research.
• SMOC (Shanghai Model Organisms Center): In January 2024, SMOC launched the U-HuDTMbase®, a comprehensive resource library of therapeutic target-humanized mouse models, covering over 600 models across various fields, including cancer, metabolism, immunology, and inflammation.

Future Prospects

The rat and mouse model market is poised for continued growth due to ongoing research across diverse sectors like healthcare, pharmaceuticals, biotechnology, and cosmetics. Animal studies play a critical role in understanding disease mechanisms and developing new treatments, despite ethical concerns surrounding their use.

In 2022, 2.76 million scientific operations involving live animals were conducted in the UK, with 1.51 million for experimental purposes and 1.25 million (45% of all procedures) for creating and breeding genetically altered (GA) animals. 

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